Suggestions by @nathanialprice

Ralph Macchio

as Mike Wheeler in Stranger Things (1986)

Score: +9

Ke Huy Quan

as Dustin Henderson in Stranger Things (1986)

Score: +6

Lea Thompson

as Nancy Wheeler in Stranger Things (1986)

Score: +1

Fionn Whitehead

as Smerdyakov in The Brothers Karamazov

Score: +1

John Hawkes

as Scarecrow in Every Batman Character

Score: +4

John Hawkes

as Dr. Jonathan Crane in Batman

Score: -1

Emilio Estevez

as Uncle Ben in Spider-Man

Score: -2

Emilio Estevez

as Ben Parker in Characters who have not appeared, but should appear, in the MCU

Score: -6

Emilio Estevez

as Ben Parker in Marvel Cinematic Universe

Score: -1

Emilio Estevez

as Ben Parker in Characters for future MCU movies

Score: +2

Damian Lewis

as Norman Osborn in Characters Not Yet in the MCU

Score: +3

Emilio Estevez

as Ben Parker in Characters Not Yet in the MCU

Score: +6

Emilio Estevez

as Ben Parker in Spider-Man

Score: +1

Emilio Estevez

as Ben Parker in Spider-Man

Score: +1

Damian Lewis

as Norman Osborn in Spider-Man

Score: -1

Linda Cardellini

as Sally Jackson in The Percy Jackson Cinematographic Universe

Score: +3