Suggestions by @agent39

Vincent D'Onofrio

as Socrates in Biopics

Score: +1

Robert Miano

as Seneca the Younger in Biopics

Score: +1

Jude Ciccolella

as Clive Staples Lewis in Biopics

Score: +1

Kiefer Sutherland

as Martin Luther in Biopics

Score: 0

John Cleese

as Job's Three Friends in The Bible

Score: +3

Sylvester McCoy

as Job's Three Friends in The Bible

Score: +3

Jim Broadbent

as Job's Three Friends in The Bible

Score: +4

Uma Thurman

as "Potiphar's Wife" in The Bible

Score: +4

Ralph Fiennes

as Potiphar in The Bible

Score: +4

Vincent Cassel

as Victor Von Doom in The Fantastic Four

Score: -6

Glenn Howerton

as Reed Richards in The Fantastic Four

Score: -18

Andrew Garfield

as Arthur Denniston in The Space Trilogy

Score: +1

Bryce Dallas Howard

as Ivy Maggs in The Space Trilogy

Score: +1

Mark Ruffalo

as Uzziah in Judith

Score: +1

Gary Sinise

as Joakim in Judith

Score: +1

John Boyega

as Achior in Judith

Score: +1

Tom Hiddleston

as Bagoas in Judith

Score: +1

Aidan Turner

as Nebuchadnezzar in Judith

Score: +1

Sigourney Weaver

as Abra in Judith

Score: +1

Sylvester Stallone

as Holofernes in Judith

Score: +1