The seemingly invincible Spider-Man goes up against an all-new crop of villains—including the shape-shifting Sandman. While Spider-Man’s superpowers are altered by an alien organism, his alter ego, Peter Parker, deals with nemesis Eddie Brock and also gets caught up in a love triangle.
Spider-Man 3 (2007) has been suggested to play 154 roles. Click below to see other actors suggested for each role, and vote for who you think would play the role best.