Misako Montgomery Garmadon is an archaeologist and a close ally of the ninja. She is Lloyd's mother, Garmadon's ex-wife, as well as Wu's sister-in-law, and the First Spinjitzu Master's daughter-in-law. Following the return of the Stone Army, Misako reunited with Wu and met the ninja, assisting them in their quest to battle the Overlord and Garmadon. After the Overlord possessed Garmadon, Lloyd fought against him during the Final Battle, seemingly destroying him while also purifying Garmadon of his evil. Misako and Lloyd then departed with Garmadon with the hope of rebuilding their lives.
Misako and Garmadon later settled down in a monastery. As of when the Nindroid crisis had begun, Misako remained at the monastery while Garmadon and Lloyd set off to face the Overlord again. After Zane's supposed demise, the ninja and Garmadon set off to a mysterious island to find their lost friend, which went unknown to Misako and Wu. Misako attempted to establish contact with them until the ninja returned along with the Elemental Masters. The new alliance fought Master Chen's army at the Corridor of Elders. In a bid to defeat them, Garmadon had himself banished to the Cursed Realm.
Due to Garmadon's banishment, Morro escaped the Cursed Realm and possessed Lloyd, setting off on a quest to claim the Realm Crystal. Misako accompanied Wu and the ninja to save her son, and they eventually succeeded in doing so.
Sometime later, the ninja were framed for crimes they didn't commit, leading Misako to be captured by the police. However, a deceptive djinn named Nadakhan trapped her in the Sword of Souls. Misako was later freed, and due to Jay's final wish, recent events were undone and she was never captured. Shortly after, Misako journeyed to the Dark Island to investigate reports of missing fishermen and ended up uncovering a diabolical plot by Clouse.
On the Day of the Departed, Pythor set off to have revenge on Lloyd, and he surprised attacked Misako and her son while they were commemorating Garmadon at the Corridor of Elders. Lloyd then fought against Pythor before he decided to leave for his own sake.
After moving into the Temple of Airjitzu and Wu being attacked by Acronix, Misako personally nursed him before he was captured and was soon lost in time. She later went on a discreet search for him, not telling anyone, not even her son before finding Wu as a baby, later being captured by the Sons of Garmadon. She reunited with Lloyd and witnessed their attempt to bring Garmadon back and were slightly successful.
Following the supposed demise of the original ninja and Wu, Misako became part of the Resistance before she was arrested during the raid on their base. Upon hearing the return of the original ninja and Wu, this inspired her and others to break out and help them restrain the Colossus.
After Faith and Firstbourne crashed down onto the Monastery of Spinjitzu's grounds, Misako helped nurse Faith back to health. She was later reunited with her resurrected husband after Garmadon joined forces with the ninja to prevent the Oni from launching their invasion.
Not long after the Prime Empire incident, Misako forced a gloomy Wu to accompany the ninja to Shintaro.
She went on an expedition to the uncharted island with Clutch Powers and Wu, unfortunately, she went missing with them. However, she was rescued by the ninja and returned to the monastery.
She later helped Wu, Ray, Kai, and Cole stop Kalmaar from acquiring the Storm Amulet so he could not reawaken Wojira. However, this was unsuccessful and Wojira was reawakened, although Nya defeated her at the cost of merging with the ocean and leaving the ninja. Misako attended her memorial.
Following the Overlord's return to Ninjago and the crystal army's invasion a year later, Misako went to the Library of Domu and retrieved the Dragon Form scroll, trying to decipher the messaging with Wu and the ninja. She then later joins the Resistance during the Final prophecy of Quanish the Elder to fight the crystal army. After the Overlord was defeated once again by Lloyd, Misako reunited with the ninja and her family as they witnessed the Golden Ultra Dragon and its departure. After that, she and many allies helped the ninja reconstruct the Monastery of Spinjitzu.
