Suggestions by @user_284781

Marty and Doc

as James Stewart and Boris Karloff in Voice actors and characters

Score: +4

Luke Skywalker and Darth Vader

as James Stewart and Boris Karloff in Voice actors and characters

Score: +4

Spider-Man and Venom

as James Stewart and Boris Karloff in Voice actors and characters

Score: +4

Tom Cat

as Lionel Barrymore in Voice actors and characters

Score: -3

SMG3

as Bela Lugosi in Characters golden age stars could have played

Score: +4

SMG4

as Boris Karloff in Characters golden age stars could have played

Score: +4

Lois Griffin and Marge Simpson

as Lucille La Verne and Elsa Lanchester in Characters golden age stars could have played

Score: +3

Homer Simpson and Peter Griffin

as Bela Lugosi and Boris Karloff in Characters golden age stars could have played

Score: +4

Peter and Lois Griffin

as Bela Lugosi and Lucille La Verne in Characters golden age stars could have played

Score: +4

Lois Griffin

as Lucille La Verne in Characters golden age stars could have played

Score: +5

Peter Griffin

as Bela Lugosi in Characters golden age stars could have played

Score: +4

Marge Simpson

as Elsa Lanchester in Characters golden age stars could have played

Score: +4

Homer Simpson

as Boris Karloff in Characters golden age stars could have played

Score: +5

Homer and Marge

as Boris Karloff and Elsa Lanchester in Characters golden age stars could have played

Score: +4

Nicole Watterson

as Elsa Lanchester in Characters golden age stars could have played

Score: +3

Richard Watterson

as Boris Karloff in Characters golden age stars could have played

Score: +4