Suggestions by @user_236147

Kevin Hart

as Ryan in American Doctor Who (2005-present)

Score: +1

Zoë Kravitz

as Yasmin in American Doctor Who (2005-present)

Score: +1

Kristen Bell

as Thirteenth Doctor in American Doctor Who (2005-present)

Score: 0

Kaley Cuoco

as Thirteenth Doctor in American Doctor Who (2005-present)

Score: -2

Brie Larson

as Thirteenth Doctor in American Doctor Who (2005-present)

Score: +2

Reese Witherspoon

as Thirteenth Doctor in American Doctor Who (2005-present)

Score: -2

Anne Hathaway

as Missy in American Doctor Who (2005-present)

Score: +1

Jodie Foster

as Missy in American Doctor Who (2005-present)

Score: +1

Dennis Quaid

as Twelfth Doctor in American Doctor Who (2005-present)

Score: +1

Kiefer Sutherland

as Twelfth Doctor in American Doctor Who (2005-present)

Score: +3

Michael Keaton

as Twelfth Doctor in American Doctor Who (2005-present)

Score: +3

Bryan Cranston

as Twelfth Doctor in American Doctor Who (2005-present)

Score: +4

Chloë Grace Moretz

as Clara Oswald in American Doctor Who (2005-present)

Score: +2

Anna Kendrick

as Clara Oswald in American Doctor Who (2005-present)

Score: +1

Elizabeth Olsen

as Clara Oswald in American Doctor Who (2005-present)

Score: +1

Emma Stone

as Clara Oswald in American Doctor Who (2005-present)

Score: +2

Julianne Moore

as River Song in American Doctor Who (2005-present)

Score: +2

Winona Ryder

as River Song in American Doctor Who (2005-present)

Score: +1

Jamie Lee Curtis

as River Song in American Doctor Who (2005-present)

Score: 0

Kate McKinnon

as River Song in American Doctor Who (2005-present)

Score: +1