Suggestions by @tip001

Stephen Graham

as Ninth Doctor in Doctor Who (Recasting Characters)

Score: -1

Georgia Tennant

as Rose Tyler in Doctor Who (Recasting Characters)

Score: -3

Carey Mulligan

as Clara Oswald in Doctor Who (Recasting Characters)

Score: 0

Felicity Jones

as Amy Pond in Doctor Who (Recasting Characters)

Score: 0

Lily Collins

as Clara Oswald in Doctor Who (Recasting Characters)

Score: 0

Emilia Clarke

as Clara Oswald in Doctor Who (Recasting Characters)

Score: +1

Emma Thompson

as The Master VII (Missy) in Doctor Who (Recasting Characters)

Score: +1

Tilda Swinton

as The Master VII (Missy) in Doctor Who (Recasting Characters)

Score: +2

Florence Pugh

as Rose Tyler in Doctor Who (Recasting Characters)

Score: +1

Domhnall Gleeson

as Tenth Doctor in Doctor Who (Recasting Characters)

Score: 0

Ellen Greene

as Sarah-Jane Smith in Doctor Who (Recasting Characters)

Score: +1

Andrew Garfield

as Tenth Doctor in Doctor Who (Recasting Characters)

Score: +4

Cate Blanchett

as River Song in Doctor Who (Recasting Characters)

Score: 0

Tamsin Greig

as The Master VII (Missy) in Doctor Who (Recasting Characters)

Score: 0

Lily Collins

as Rose Tyler in Doctor Who (Recasting Characters)

Score: 0

Kaya Scodelario

as Rose Tyler in Doctor Who (Recasting Characters)

Score: 0

Lara Pulver

as River Song in Doctor Who (Recasting Characters)

Score: +1

Lena Headey

as River Song in Doctor Who (Recasting Characters)

Score: +2

Anna Friel

as River Song in Doctor Who (Recasting Characters)

Score: +1

Miranda Raison

as Rose Tyler in Doctor Who (Recasting Characters)

Score: +2