Suggestions by @theallseeing

Viola Davis

as Dr Octopus in Genderswap Spiderman Villains

Score: 0

Amanda Seyfried

as Sally Goodman in Breaking Bad (Genderswap)

Score: +1

Natalia Dyer

as The Girl in Girl With No Name

Score: -6

Penn Badgley

as Jim McBane in Girl With No Name

Score: +4

Eddie Redmayne

as John "Jack" Starbright in Alex Rider (Genderswap)

Score: +1

Anya Taylor-Joy

as Diana Burnwood in Hitman: Origins

Score: +1

Jane Perry

as Married Couple - Wife in Hitman: Origins

Score: +2

Laura Linney

as Robert Callaghan in Big Hero 6 (Genderswap)

Score: 0

Veronica Falcón

as Gabriela Fring in Breaking Bad (Genderswap)

Score: +1

Sofia Hublitz

as Jessica "Jessie" Pinkman in Breaking Bad (Genderswap)

Score: 0

Julia Garner

as Jessica "Jessie" Pinkman in Breaking Bad (Genderswap)

Score: +3

Carmen Bicondova

as Jessica "Jessie" Pinkman in Breaking Bad (Genderswap)

Score: 0

Laura Linney

as Wendy White in Breaking Bad (Genderswap)

Score: +5

Emma Roberts

as Brittany Ashby in You (Genderswap)

Score: +1

Keith David

as Redfield in It Lives in the Woods

Score: +1

Laura Linney

as Professor Callaghan/Yokai in Big Hero 6 (Genderswap)

Score: +1

Gemma Chan

as Jiao in Hitman

Score: +4

Emma Watson

as Penelope Graves in Hitman

Score: +4

Margarita Levieva

as Tamara Vidal in Hitman

Score: +1

Helen Mirren

as Alexa Carlisle in Hitman

Score: +3