Suggestions by @svendragelj

Tobey Maguire

as Eleventh Doctor in What If Doctor Who Was American?

+5-7Score: -2

Jensen Ackles

as Tenth Doctor in What If Doctor Who Was American?

+8-8Score: 0

John Cusack

as Ninth Doctor in What If Doctor Who Was American?

+7-0Score: +7

Mel Gibson

as Eighth Doctor in What If Doctor Who Was American?

+3-7Score: -4

Joe Pesci

as Seventh Doctor in What If Doctor Who Was American?

+4-3Score: +1