Suggestions by @randomcaster

Johnny English

as Rowan Atkinson in Best character each of these actors played

Timon

as Nathan Lane in Best character each of these actors played

The Genie

as James Monroe Iglehart in Best character each of these actors played

Alastor (Hazbin Hotel)

as Edward Bosco in Best character each of these actors played

Angel Dust (Hazbin Hotel)

as Michael Kovach in Best character each of these actors played

Pigeon

as Norm Macdonald in Best character each of these actors played

Gary Goodspeed

as Olan Rogers in Best character each of these actors played

The Penguin (Oswald Cobblepot)

as Colin Farrell in Best character each of these actors played

Gollum

as Andy Serkis in Best character each of these actors played

Sasha Waybright

as Anna Akana in Best character each of these actors played

Sprig Plantar

as Justin Felbinger in Best character each of these actors played

Marcy Wu

as Haley Tju in Best character each of these actors played

Anne Boonchuy

as Brenda Song in Best character each of these actors played

Dr. Facilier

as Keith David in Best character each of these actors played

Hades

as James Woods in Best character each of these actors played

Frank The Plant

as J.B. Smoove in Best character each of these actors played

Harley Quinn (Dr. Harleen Quinzel)

as Kaley Cuoco in Best character each of these actors played

Doctor Psycho

as Tony Hale in Best character each of these actors played

John Wick

as Keanu Reeves in Best character each of these actors played

Buzz Lightyear

as Tim Allen in Best character each of these actors played