Suggestions by @quinnwalton

Rosamund Pike

as Sue Storm in Fantastic Four

Score: -1

Rose McIver

as Sue Storm in Fantastic Four

Score: +1

Yvonne Strahovski

as Sue Storm in Fantastic Four

Score: +1

Jason Sudeikis

as Reed Richards in Fantastic Four

Score: -1

Jensen Ackles

as Reed Richards in Fantastic Four

Score: -1

Glenn Howerton

as Reed Richards in Fantastic Four

Score: +5

Bill Pullman

as Commissioner Gordon in The DCU

Score: +1

Ethan Cutkosky

as Johnny Storm/ Human torch in Mcu fantastic four my cast

Score: +1

Rosamund Pike

as Susan Storm/invisible woman in Mcu fantastic four my cast

Score: +3

Yvonne Strahovski

as Susan Storm/invisible woman in Mcu fantastic four my cast

Score: +1

Rose McIver

as Susan Storm/invisible woman in Mcu fantastic four my cast

Score: +1

Glenn Howerton

as Reed Richards/Mister Fantastic in Mcu fantastic four my cast

Score: +1

Rami Malek

as Doctor Doom in Mcu fantastic four my cast

Score: +1

Wagner Moura

as Doctor Doom in Mcu fantastic four my cast

Score: 0

Rami Malek

as The Joker in The DCU

Score: -1

Edward Norton

as Lex Luthor in The DCU

Score: +2

Taron Egerton

as Batman in The DCU

Score: -3

Jason Isaacs

as Mysterio in Spider-Man universe

Score: +2

Hugh Laurie

as Mysterio in Spider-Man universe

Score: +1

Corey Stoll

as Vulture in Spider-Man universe

Score: 0