Suggestions by @otsutsuki

Glenn Close

as Nova Prime in Nova

Score: +2

Johnny Depp

as Actors in Actors who could play Doctor Doom in the MCU

Score: -4

Nikolaj Coster-Waldau

as Actors in Actors who could play Doctor Doom in the MCU

Score: +2

Mahershala Ali

as Eric Brooks in Blade

Score: +3

Wesley Snipes

as Jamal Afari in Blade

Score: +2

Nikolaj Coster-Waldau

as Deacon Frost in Blade

Score: +2

Emma Mackey

as Rachel Van Helsing in Blade

Score: +2

Paul Wesley

as Hannibal King in Blade

Score: +2

Vanessa Morgan

as Dr. Karen Jenson in Blade

Score: +2

Tichina Arnold

as Tara Brooks in Blade

Score: 0

Antony Starr

as Dracula in Blade

Score: +1

Emily VanCamp

as Sharon Carter in Blade

Score: +1

Jeffrey Dean Morgan

as Abraham Whistler in Blade

Score: +1

Hans Zimmer

as Composer in Blade

Score: +1

Michael Wilkinson

as Costume Designer in Blade

Score: +1

Jennifer Lame

as Editor in Blade

Score: +1

Greig Fraser

as Cinematography in Blade

Score: +1

Kevin Feige

as Producer in Blade

Score: +1

Winona Ryder

as Eliza in Blade

Score: +1

Benedict Wong

as Wong in Blade

Score: +1