Suggestions by @odonnellii

Sonoya Mizuno

as Jasnah Kholin in The Way of Kings

Score: -7

Constance Wu

as Jasnah Kholin in The Way of Kings

Score: -10

Barry Keoghan

as Renarin Kholin in The Way of Kings

Score: +3

Élodie Yung

as Jasnah Kholin in The Way of Kings

Score: +34

Gary Oldman

as Senator Mitch McConnell in Ford and Kavanaugh

Score: +1

Cliff Simon

as Ra's al Ghul in Batman (Arrowverse)

Score: -1

Victoria Pedretti

as Vin Venture in The Mistborn Trilogy

Score: -21

Gregg Turkington

as Oswald Cobblepot in Batman (Arrowverse)

Score: +2

Vincent Kartheiser

as Edward Nygma in Batman (Arrowverse)

Score: -1

Gillian Jacobs

as Harleen Quinzel in Batman (Arrowverse)

Score: +1

Charles Dance

as Alfred Pennyworth in Batman (Arrowverse)

Score: +2

Justin Theroux

as Bruce Wayne in Batman (Arrowverse)

Score: 0

Cailee Spaeny

as Vin Venture in The Mistborn Trilogy

Score: +19

Carrie Coon

as Tony Stark in Marvel Comics (Gender Swap)

Score: -14

Maika Monroe

as Daniel Rand in Marvel Comics (Gender Swap)

Score: +2

Amanda Tapping

as Hank Pym in Marvel Comics (Gender Swap)

Score: -5

Rebecca Ferguson

as Stephen Strange in Marvel Comics (Gender Swap)

Score: +27

Gugu Mbatha-Raw

as T'Challa in Marvel Comics (Gender Swap)

Score: -2

Christopher Judge

as Thanos in Alternate MCU

Score: +7