Suggestions by @mrnotsure

Ioan Gruffudd

as Reed Richards in The Fantastic 4 : Rise of Galactus (2008)

Score: +1

Michael Douglas

as Victor Von Doom in The Fantastic 4 : Rise of Galactus (2008)

Score: +1

Doug Jones

as Silver Surfer in The Fantastic 4 : Rise of Galactus (2008)

Score: +1

Liam Neeson

as Galactus in The Fantastic 4 : Rise of Galactus (2008)

Score: +1

Jeff Bridges

as Obadiah Stane in Iron Man (2007)

Score: +1

Samuel L. Jackson

as Nick Fury (Cameo) in Iron Man (2007)

Score: +1

Gwyneth Paltrow

as Pepper Pots in Iron Man (2007)

Score: +1

Don Cheadle

as James Rhodes in Iron Man (2007)

Score: +1

Johnny Depp

as Tony Stark in Iron Man (2007)

Score: +1

David Bautista

as Shocker in Spiderman 3 (2007)

Score: +1

Kirsten Dunst

as Mary Jane Watson in Spiderman 3 (2007)

Score: +1

Topher Grace

as Venom in Spiderman 3 (2007)

Score: +1

J.K. Simmons

as J. Jonah Jameson in Spiderman 3 (2007)

Score: +1

James Franco

as Harry Osborn in Spiderman 3 (2007)

Score: +1

Seth Green

as Ned Leeds in Spiderman 3 (2007)

Score: +1

Sally Field

as Aunt May in Spiderman 3 (2007)

Score: +1

Tobey Maguire

as Spiderman in Spiderman 3 (2007)

Score: +1

James Franco

as Harry Osborn in Spiderman 2 (2003)

Score: +1

Jack Black

as MODOK in Ant-Man (2006)

Score: +1

Marisa Tomei

as Janet Van Dyne in Ant-Man (2006)

Score: +1