Suggestions by @michelewitham

Eric 'Butterbean' Esch

as KIng Hippo in Punch Out

Score: +2

Vin Diesel

as Bald Bull in Punch Out

Score: +1

Scarlett Johansson

as Mom in Punch Out

Score: +1

Daniel Dae Kim

as Piston Hondo in Punch Out

Score: +1

Conor McGregor

as Aran Ryan in Punch Out

Score: +1

Jack Black

as Bear Hugger in Punch Out

Score: +1

Zendaya

as Girlfrend in Punch Out

Score: +1

Mike Tyson

as Mike Tyson in Punch Out

Score: +1

Jason Momoa

as Great Tiger in Punch Out

Score: 0

Samuel L. Jackson

as Doc Louis in Punch Out

Score: +2

Dwayne Johnson

as Uncle in Punch Out

Score: +1

Michael B. Jordan

as Disco kid in Punch Out

Score: +2

Tom Holland

as Little Mac in Punch Out

Score: -2