Suggestions by @mattkid

Elijah Wood

as Shocker in Sony’s Sinister Six

Score: +1

Andrei Arlovski

as Rhino in Sony’s Sinister Six

Score: -1

Leslie Grace

as Beetle in Sony’s Sinister Six

Score: +2

Jonathan Majors

as Norman Osborn in Sony’s Sinister Six

Score: -4

Shameik Moore

as Harry Osborn in Sony’s Sinister Six

Score: -2

Andie MacDowell

as Aunt May in Sony’s Sinister Six

Score: -1

Camila Mendes

as Mary Jane Watson in Sony’s Sinister Six

Score: 0

Joe Keery

as Spider Man in Sony’s Sinister Six

Score: -1

Emma Stone

as Gwen Stacy in Sony’s Sinister Six

Score: +2

Issac Ryan Brown

as Spider-Man in Sony’s Sinister Six

Score: +3

Issac Ryan Brown

as Spider Man in Sony’s Sinister Six

Score: +3

John Cena

as Sandman in Sony’s Sinister Six

Score: +6

Christopher Judge

as Ubu in James Gunn's DC Cinematic Universe

Score: +2

Ghassan Massoud

as Ra's al ghul in James Gunn's DC Cinematic Universe

Score: +7

Ghassan Massoud

as Ra's al Ghul in The Brave and the Bold

Score: +1

Emmanuelle Chriqui

as Thalia al Ghul in The Brave and the Bold

Score: +1

Emmanuelle Chriqui

as Talia al Ghul in James Gunn's DC Cinematic Universe

Score: +1

Javon Walton

as Damian Wayne in James Gunn's DC Cinematic Universe

Score: +10

Harry Lennix

as Martian Manhunter in James Gunn's DC Cinematic Universe

Score: -2

Tim Blake Nelson

as Parasite in James Gunn's DC Cinematic Universe

Score: +4