Suggestions by @ltsfox

Isabella merced

as Harlowe in Borderlands

Score: -1

Sadie Sink

as Gaige in Borderlands

Score: +1

Ella Purnell

as Maya in Borderlands

Score: +1

Steven Lang

as General Knox in Borderlands

Score: +1

David Tennant

as Handsome Jack in Borderlands Film (Better Cast)

Score: +1

Vinnie Jones

as Mister Torgue in Borderlands

Score: +1

John Cena

as Piston in Borderlands

Score: +1

Daniel Brühl

as Wilhelm in Borderlands

Score: +1

Sonny Kendall

as Davis Pickle in Borderlands

Score: +1

Nell Fisher

as Tiny Tina (young) in Borderlands

Score: +1

Priyanka Chopra Jonas

as Lakshmi-2/Maya Sundaresh/The Conductor in Destiny

Score: +1

Bradley Cooper

as Axton in Borderlands

Score: +1

Zendaya

as Anastacia Bray in Destiny

Score: +1

Simu Liu

as Shaw Han in Destiny

Score: +1

Brenda Fricker

as Eva Levante in Destiny

Score: +1

Anthony Hopkins

as Clovis Bray in Destiny

Score: +1

Christoph Waltz

as The Witness in Destiny

Score: +1

Brie Larson

as Guardian Titan in Destiny

Score: +1

Oded Fehr

as Osiris in Destiny

Score: +1

Lennie James

as Lord Shaxx in Destiny

Score: +1