Suggestions by @kissmethardy

Eiza González

as Lois Lane in Superman Legacy

Score: +1

Sam Neill

as Perry White in Superman Legacy

Score: +1

Kate Siegel

as Susan Storm in The Fantastic Four

Score: -1

Olivia Wilde

as Susan Storm in The Fantastic Four

Score: -1

Oliver Jackson-Cohen

as Victor Von Doom in The Fantastic Four

Score: -2

Rahul Kohli

as Reed Richards in The Fantastic Four

Score: -1

Rory Scovel

as H.E.R.B.I.E in The Fantastic Four

Score: -1

Dacre Montgomery

as Johnny Storm in The Fantastic Four

Score: -1

John Cena

as Ben Grimm in The Fantastic Four

Score: -1

Jack Black

as Harvey Elder in The Fantastic Four

Score: 0

Kevin Hart

as Mister Mxyzptlk in A Movie About Superman That Doesn't Have Superman In The Title

Score: +1

Billy Connolly

as Duncan in Macbeth

Score: +3