Suggestions by @king_niteli

Kevin Spacey

as Richard Chesler in Fightclub

Score: +1

Vincent D'Onofrio

as Robert 'bob' Paul in Fightclub

Score: +1

Ariel Winter

as Meg Griffin in Cartoon Children/Teens

Score: +2

Jeremy Ray Taylor

as Chris Griffin in Cartoon Children/Teens

Score: +1

Robert De Niro

as Grandpa Abe Simpson in Cartoon Grandparents

Score: +1

Jacob Tremblay

as Timmy Turner in Cartoon Children/Teens

Score: +2

Timothée Chalamet

as Danny Fentom in Cartoon Children/Teens

Score: +1

John Leguizamo

as Jack Harris in Cartoon Dads

Score: +1

Mary Elizabeth Winstead

as Paige Tillerman in Cartoon Moms

Score: +1

Zoe Kazan

as Nicole Watterson in Cartoon Moms

Score: -1

Macey Estrella-Kadlec

as Annie Harris in Cartoon Moms

Score: 0

Lucy Liu

as Yuki Yoshida in Cartoon Moms

Score: +2