Suggestions by @killpino

Ralph Fiennes

as Dmitri Smerdyakov in Spider-Man 3

Score: +1

Bill Hader

as Quentin Beck in Spider-Man 3

Score: +1

David Tennant

as The Lizard in Spider-Man 3

Score: +1

Winona Ryder

as Aunt May in Spider-Man 3

Score: +1

Florence Pugh

as Gwen Stacy in Spider-Man 3

Score: +1

Jack Quaid

as Harry Osborn in Spider-Man 3

Score: +1

Brenton Thwaites

as Spider-Man in Spider-Man 3

Score: +1

David Tennant

as Dr. Curt Connors in Spider-Man 2

Score: +1

Jon Hamm

as Nick Fury in Spider-Man 2

Score: +1

Mel Gibson

as J. Jonah Jameson in Spider-Man 2

Score: +1

David Morrissey

as Norman Osborn in Spider-Man 2

Score: +1

Ralph Fiennes

as Chameleon in Spider-Man 2

Score: +1

Bill Hader

as Mysterio in Spider-Man 2

Score: +1

Winona Ryder

as Aunt May in Spider-Man 2

Score: +1

Florence Pugh

as Gwen Stacy in Spider-Man 2

Score: +1

Jack Quaid

as Harry Osborn in Spider-Man 2

Score: +1

Brenton Thwaites

as Spider-Man in Spider-Man 2

Score: +1

Cillian Murphy

as Bruce Banner in MCU Reboot: Spider-Man

Score: +1

Octavia Spencer

as Shirley Bennett in Community Reboot

Score: +1

John Cho

as Ben Chang in Community Reboot

Score: +1