Suggestions by @kedamour

Jodie Sweetin

as Susan Storm in Fantastic Four

Score: 0

Kristen Bell

as Alicia Masters in Fantastic Four

Score: +1

Jackie Earle Haley

as Doctor Doom in Fantastic Four

Score: +1

John Stamos

as Mr. Fantastic in Fantastic Four

Score: +1

Bobcat Goldthwait

as Meta Man in The Incredibles

Score: +1

Whoopi Goldberg

as Esme Winikus in batman in the MCU

Score: +1

Bobcat Goldthwait

as Suspect 5 in Scooby Doo: Mystery Madness

Score: +1

Zendaya

as MJ in batman in the MCU

Score: +1

Tom Holland

as Spiderman in batman in the MCU

Score: +2

Adrian Scarborough

as Barron Von Redberry in Breakfast Cereal Cinematic Universe

Score: +1

John Lithgow

as Sir Grapefellow in Breakfast Cereal Cinematic Universe

Score: +1

Jeff Daniels

as Sheriff Quick Draw McGraw in Breakfast Cereal Cinematic Universe

Score: +1

Bobcat Goldthwait

as Klondike Pete in Breakfast Cereal Cinematic Universe

Score: +1

Bobcat Goldthwait

as The Penguin in Todd Phillips' The Batman

Score: +1

Louie Anderson

as Rupert Thorne in batman in the MCU

Score: +1

Chris Noth

as Agent John Davis in batman in the MCU

Score: +1

Aidan Gallagher

as Richard Grayson in batman in the MCU

Score: +6

Violet Brinson

as Mary Beth Kane in batman in the MCU

Score: +4

John Goodman

as James Gordon in batman in the MCU

Score: +2

Joseph Marcell

as Alfred in batman in the MCU

Score: +3