Suggestions by @kateburger

Uma Thurman

as Nora Osborn in DC & Marvel (Genderswap)

Rachel Weisz

as Bryce Banner in DC & Marvel (Genderswap)

Jodie Comer

as Joker in DC & Marvel (Genderswap)

Rebecca Ferguson

as Holly Jordan in DC & Marvel (Genderswap)

Sam Claflin

as Sam Storm in DC & Marvel (Genderswap)

Cheyenne Jackson

as Hell in DC & Marvel (Genderswap)

Cobie Smulders

as Petty Quill in DC & Marvel (Genderswap)

Carla Gugino

as Tanya Stark in DC & Marvel (Genderswap)

Uma Thurman

as Green Goblin in Ultimate Spider-Man (Live action)

Cobie Smulders

as Peter Quill in Marvel Comics (Gender Swap)

Thomasin McKenzie

as Peter Parker in Marvel Comics (Gender Swap)

Salma Hayek

as Ra's al Ghul in DC Comics (Gender Swap)

Tina Fey

as James Gordon in DC Comics (Gender Swap)

Hayley Atwell

as Bruce Wayne in DC Comics (Gender Swap)

Tom Hiddleston

as Selina Kyle in DC Comics (Gender Swap)

Natalia Dyer

as Jason Todd in DC Comics (Gender Swap)

Lana Parrilla

as Kal-El, Clark Kent in DC Comics (Gender Swap)

Hayley Atwell

as Jonathan Harker in Dracula (Gender Swap)

Liv Tyler

as Count Dracula in Dracula (Gender Swap)

Tilda Swinton

as Vision in Genderswap Marvel