Suggestions by @jamesthethinker

Pocahontas

as Secretary of the Interior in Building the ultimate fictional US Presidential Cabinet

Score: +1

Leonard McCoy

as Secretary of Health and Human Services in Building the ultimate fictional US Presidential Cabinet

Score: +1

Cordell Walker

as Secretary of Homeland Security in Building the ultimate fictional US Presidential Cabinet

Score: +1

Villager

as Secretary of Agriculture in Building the ultimate fictional US Presidential Cabinet

Score: +1

George Bailey

as Secretary of Housing and Urban Development in Building the ultimate fictional US Presidential Cabinet

Score: +1

Jennifer Honey

as Secretary of Education in Building the ultimate fictional US Presidential Cabinet

Score: +1

Scrooge McDuck

as Secretary of the Treasury in Building the ultimate fictional US Presidential Cabinet

Score: +1

Hal Smith

as Santa Claus in Best Voices of Animated Characters

Score: +1

William Salyers

as Doctor Octopus in Best Voices of Animated Characters

Score: +3

Pat Stevens

as Velma Dinkley in Best Voices of Animated Characters

Score: +1

Jason Aldean

as King of The Hill in Actors and Actresses Who Should Be in Animated Series/Cartoons

Score: +1

Shaboozey

as King of The Hill in Actors and Actresses Who Should Be in Animated Series/Cartoons

Score: +1

James Sie

as Sun Chained-in-Ink in DC Trinity: Arcana

Score: +1

Silent character

as Ace in DC Trinity: Arcana

Score: +1

Maggie Q

as Wonder Woman in DC Trinity: Arcana

Score: +3

Jim Caviezel

as Batman in DC Trinity: Arcana

Score: +1

Jack Quaid

as Superman in DC Trinity: Arcana

Score: +3

Wilmer Valderrama

as Gangbuster in DC Trinity: Arcana

Score: +1

Claudia Black

as Morgaine le Fey in DC Trinity: Arcana

Score: +1

Corey Burton

as Brainiac in DC Trinity: Arcana

Score: +2