Suggestions by @iamanerd

Tom Everett Scott

as Aunt May in Spider-Man: No Way Home (Gender Swapped)

Score: +1

Daniel Craig

as Professor X in X-Men in the MCU

Score: -5

Sophie Turner

as Jaz Fenton in Danny Phantom

Score: +1

Julianne Moore

as Maddie Fenton in Danny Phantom

Score: +1

Bruce Campbell

as Jack Fenton in Danny Phantom

Score: +1

Caleb McLaughlin

as Tucker in Danny Phantom

Score: +1

Malina Weissman

as Sam in Danny Phantom

Score: +1

Asher Angel

as Danny Phantom in Danny Phantom

Score: +1

John Krasinski

as Director in Danny Phantom

Score: +1

Psych

as Best TV Show in MyCast Awards

Score: +4

Michael Palin

as Dupin in The League of Extraordinary Gentlemen

Score: +1

Richard Ayoade

as Sherlock Holmes in The League of Extraordinary Gentlemen

Score: +1

Matthew Goode

as Mr Bond in The League of Extraordinary Gentlemen

Score: +1

Jeffrey Wright

as Mycroft Holmes in The League of Extraordinary Gentlemen

Score: +1

Andy Lau

as Devil Doctor in The League of Extraordinary Gentlemen

Score: +1

Martin Freeman

as James Moriarty in The League of Extraordinary Gentlemen

Score: +1

John Leguizamo

as Invisible Man in The League of Extraordinary Gentlemen

Score: +1

James D'Arcy

as Dr Jekyll in The League of Extraordinary Gentlemen

Score: +1

Aasif Mandvi

as Captain Nemo in The League of Extraordinary Gentlemen

Score: +1

Maisie Richardson-Sellers

as Mina Harker in The League of Extraordinary Gentlemen

Score: +1