Suggestions by @georgiafan64

Gal Gadot

as Sherlock Holmes in Femlock

Score: -2

Claire Foy

as Sherlock Holmes in Femlock

Score: +1

Cate Blanchett

as Sherlock Holmes in Femlock

Score: -2

Carey Mulligan

as Dr. Joan Watson in Femlock

Score: +1

Phoebe Waller-Bridge

as Sherlock Holmes in Femlock

Score: +1

Keira Knightley

as Sherlock Holmes in Femlock

Score: +1

Cillian Murphy

as Bond Villain in Bond 26

Score: +2

Phoebe Waller-Bridge

as Q in Bond 26

Score: +1

Keira Knightley

as Bond Girl in Bond 26

Score: +3

Keira Knightley

as The Love Interest in Bond 26

Score: +2

Martin Freeman

as The Villain in Bond 26

Score: 0

Gary Oldman

as M in Bond 26

Score: +1

Carey Mulligan

as Dr Jane Watson in Sherlock Holmes(genderswap)

Score: +4

Keira Knightley

as Sherlize Holmes in Sherlock Holmes(genderswap)

Score: 0

Christopher Nolan

as Director in Bond 26

Score: +1

Aaron Taylor-Johnson

as James Bond in Bond 26

Score: +1

Alison Brie

as Bond Girl in Bond 26

Score: +1

Claire Foy

as Moneypenny in Bond 26

Score: +1

Asa Butterfield

as Q in Bond 26

Score: +1

Kenneth Branagh

as M in Bond 26

Score: +1