Suggestions by @frankentrapta

Vincent Price

as Mr. Boddy in Clue (1950)

Score: +1

Peter Lorre

as Mr. Green in Clue (1950)

Score: +1

Edward Van Sloan

as Professor Plum in Clue (1950)

Score: +1

Anna May Wong

as Ms. Scarlet in Clue (1950)

Score: +1

Edward Van Sloan

as Professor Plum in Clue (1943)

Score: +4

Una O'Connor

as The Cook in Clue (1943)

Score: +1

Una O'Connor

as Mrs. White in Clue (1943)

Score: +1

Lionel Atwill

as Colonel Mustard in Clue (1943)

Score: -1

Anna May Wong

as Miss Scarlett in Clue (1943)

Score: +3

Vincent Price

as Wadsworth / The Real Mr. Boddy in Clue (1943)

Score: +1

Peter Lorre

as Kamek in The Super Mario Bros. (1950 film)

Score: +8

Harry Earles

as Toad in The Super Mario Bros. (1950 film)

Score: -3

Haruo Nakajima

as Bowser (suit acting) in The Super Mario Bros. (1950 film)

Score: +6

Bud Abbott

as Luigi in The Super Mario Bros. (1950 film)

Score: +7

Lou Costello

as Mario in The Super Mario Bros. (1950 film)

Score: +7

LeVar Burton

as Mr. Green in Hasbro Games Cinematic Universe (Animated)

Score: +1

Mohan Kapur

as Professor Plum in Hasbro Games Cinematic Universe (Animated)

Score: +1

Dev Patel

as Professor Plum in Hasbro Games Cinematic Universe (Animated)

Score: +1

Ravi Patel

as Professor Plum in Hasbro Games Cinematic Universe (Animated)

Score: +1

Sumalee Montano

as Scarlet in Hasbro Games Cinematic Universe (Animated)

Score: +1