Suggestions by @filipnikolicx

Eddie Redmayne

as Dr. Johnathon Ohnn in Fancasting Spider-Man villains in MCU

Score: +1

Eddie Redmayne

as Spot in Sam Raimi’s Uncasted Spider-Man Characters

Score: +1

Allison Janney

as Vanessa Fisk in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

P.J Heywood

as Carnage in Sam Raimi's Spider-Man Voice Casting video games Heroes and Villains

Score: -1

Sean Patrick Flanery

as Sin-Eater in Raimiverse Spider-Man Casting Heroes and Villains

Score: 0

Matthew Lillard

as Carnage in Raimiverse Spider-Man Casting Heroes and Villains

Score: +4

Bruce Campbell

as Mysterio in Daredevil Heroes and Villains Casting

Score: +1

Keith David

as Tombstone in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Brian Tee

as Mr. Negative in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Angela V. Shelton

as Calypso in Sam Raimi's Spider-Man Voice Casting video games Heroes and Villains

Score: +1

Lena Headey

as Lady Octopus in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Tim DeZarn

as Philip Watson in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Taylor Gilbert

as Madeline Watson in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Emily Blunt

as Gayle Watson in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Kristen Bell

as Anne Weying in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Brad Dourif

as Demogoblin in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Robert De Niro

as Silvermane in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1

Winona Ryder

as Vanessa Fisk in Raimiverse Spider-Man Casting Heroes and Villains

Score: -1

Ayelet Zurer

as Vanessa Fisk in Raimiverse Spider-Man Casting Heroes and Villains

Score: -1

Will Poulter

as Dylan Brock in Raimiverse Spider-Man Casting Heroes and Villains

Score: +1