Suggestions by @crowbus940

Emperor Sheev Palpatine (Darth Sidious)

as Characters in What characters do Michael Wincott needs to play

Nicole Kidman

as Actors for Evil Na'vi Antagonist in List of Actors for Evil Na'vi Villain in Avatar the Seed Bearer

Ultron

as Characters in What characters do Michael Wincott needs to play

Red Skull (Johann Schmidt)

as Characters in What characters do Michael Wincott needs to play

Hugo Weaving

as Actors for Evil Na'vi Antagonist in List of Actors for Evil Na'vi Villain in Avatar the Seed Bearer

Green Goblin (Norman Osborn)

as Characters in What characters do Michael Wincott needs to play

Bowser

as Characters in What characters do Michael Wincott needs to play

Jafar

as Characters in What characters do Michael Wincott needs to play

The Riddler (Edward Nigma)

as Characters in What characters do Michael Wincott needs to play

Mr. Freeze (Dr. Victor Fries)

as Characters in What characters do Michael Wincott needs to play

Lex Luthor

as Characters in What characters do Michael Wincott needs to play

Chameleon (Dmitri Smerdyakov)

as Characters in What characters do Michael Wincott needs to play

Jigsaw (Marvel)

as Characters in What characters do Michael Wincott needs to play

The Jigsaw Killer

as Characters in What characters do Michael Wincott needs to play

Electro (Max Dillon)

as Characters in What characters do Michael Wincott needs to play

The Joker

as Characters in What characters do Michael Wincott needs to play

Jon Hamm

as Actors for Evil Na'vi Antagonist in List of Actors for Evil Na'vi Villain in Avatar the Seed Bearer

Christian Bale

as Actors for Evil Na'vi Antagonist in List of Actors for Evil Na'vi Villain in Avatar the Seed Bearer

Ralph Fiennes

as Actors for Evil Na'vi Antagonist in List of Actors for Evil Na'vi Villain in Avatar the Seed Bearer

Henry Cavill

as Actors for Evil Na'vi Antagonist in List of Actors for Evil Na'vi Villain in Avatar the Seed Bearer