Suggestions by @conradsovet

Joaquin Phoenix

as Cancerous Rodent in ULTRAKILL

Score: +2

Sharlto Copley

as Something Wicked in ULTRAKILL

Score: +1

Tommy Wiseau

as Flesh Prison in ULTRAKILL

Score: +1

Karen Fukuhara

as Idol in ULTRAKILL

Score: +1

Ron Perlman

as The Leviathan in ULTRAKILL

Score: +2

Mads Mikkelsen

as The Ferryman in ULTRAKILL

Score: +1

Dave Bautista

as Sisyphean Insurrectionist in ULTRAKILL

Score: +1

Giancarlo Esposito

as Minos Prime in ULTRAKILL

Score: +1

Giancarlo Esposito

as The Corpse of King Minos in ULTRAKILL

Score: +1

Jake Gyllenhaal

as V2 in ULTRAKILL

Score: +2

Hideo Kojima

as Hideous Mass in ULTRAKILL

Score: +3

LeBron James

as Cerberus in ULTRAKILL

Score: +3

Dwayne Johnson

as Malicious Face in ULTRAKILL

Score: +2

Adam Driver

as Swordsmachine in ULTRAKILL

Score: +1

Christian Bale

as Gabriel in ULTRAKILL

Score: +4

Ryan Gosling

as V1 in ULTRAKILL

Score: +3