Suggestions by @ciclopexmen

George Lucas

as Director in Fantastic Four

Score: +1

Jack Black

as Ben Grimm in Fantastic Four

Score: +1

Steven Spielberg

as Director in Fantastic Four

Score: +1

Virginia Madsen

as Gwen Stacy in Spider-Man (1980s)

Score: +1

Virginia Madsen

as Mary Jane Watson in Spider-Man (1980s)

Score: +1

Dee Wallace

as Black Cat in Spider-Man (1980s)

Score: +2

Christopher Lloyd

as Doctor octopus in Spider-Man (1980s)

Score: +1

Kevin Bacon

as Harry Osborne in Spider-Man (1980s)

Score: +1

Kevin Bacon

as Flash Thompson in Spider-Man (1980s)

Score: +1

Arnold Schwarzenegger

as The sandman in Spider-Man (1980s)

Score: +1

Ralph Macchio

as Spider-Man in Spider-Man (1980s)

Score: +1

Carrie Fisher

as Black Cat in Spider-Man (1980s)

Score: +1

Karen Allen

as Black Cat in Spider-Man (1980s)

Score: +1

Margot Kidder

as Black Cat in Spider-Man (1980s)

Score: +1

Rebecca De Mornay

as Black Cat in Spider-Man (1980s)

Score: +2

Helen Slater

as Black Cat in Spider-Man (1980s)

Score: +1

Madonna

as Black Cat in Spider-Man (1980s)

Score: +1

Steven Spielberg

as Director in Spider-Man (1980s)

Score: 0

Karen Allen

as Betty Brant in Spider-Man (1980s)

Score: +1

Carrie Fisher

as Betty Brant in Spider-Man (1980s)

Score: +1