Suggestions by @audreyohare

Shailene Woodley

as Earth 928 Mary Jane Watson in Marc Webb's Spiderverse Cinematic Universe

Score: +1

Jon Hamm

as Spider-Man Noir in Marc Webb's Spiderverse Cinematic Universe

Score: +1

Dylan O'Brien

as Scarlet Spider in Marc Webb's Spiderverse Cinematic Universe

Score: +1

Armie Hammer

as 616 Shocker in Marc Webb's Spiderverse Cinematic Universe

Score: +1

Mark Harmon

as Earth 65 Captain George Stacy in Marc Webb's Spiderverse Cinematic Universe

Score: +1

Sally Field

as 616 Aunt May in Marc Webb's Spiderverse Cinematic Universe

Score: +1

Grant Gustin

as 616 Peter Parker in Marc Webb's Spiderverse Cinematic Universe

Score: +2

Thomas Brodie-Sangster

as Spider-UK in Marc Webb's Spiderverse Cinematic Universe

Score: +1

Chris Wood

as 616 Harry Osborn in Marc Webb's Spiderverse Cinematic Universe

Score: +1

Jake Gyllenhaal

as 616 Mysterio in Marc Webb's Spiderverse Cinematic Universe

Score: +1

J.K. Simmons

as J Jonah Jameson in Spider-Man (2007)

Score: +1

Martin Sheen

as Ben Parker in Spider-Man (2007)

Score: +1

Meryl Streep

as May Parker in Spider-Man (2007)

Score: +1

Danny Glover

as Robbie Robertson in Spider-Man (2007)

Score: +1

Andrew Garfield

as Spider-Man in Spider-Man (2012)

Score: +2

Chris Wood

as Harry Osborn in Spider-Man (2007)

Score: +1

Jason Isaacs

as Norman Osborn in Spider-Man (2007)

Score: +1

Emma Stone

as MJ Watson in Spider-Man (2007)

Score: +1

Andrew Garfield

as Peter Parker in Spider-Man (2007)

Score: +2

Megan Fox

as Scarlet Witch in Marc Webb's Marvel Cinematic Universe

Score: -1