Suggestions by @audreyohare

Emma Stone

as April O' Neil in Teenage Mutant Ninja Turtles Live Action

Score: +2

Tom Hiddleston

as Leo in Teenage Mutant Ninja Turtles Live Action

Score: -2

Seth Rogen

as Leo in Teenage Mutant Ninja Turtles Live Action

Score: -2

Andrew Garfield

as Leo in Teenage Mutant Ninja Turtles Live Action

Score: +2

John Wesley Shipp

as Henry Allen in The Flash DCEU

Score: +1

Kyle Chandler

as Kyle West in The Flash DCEU

Score: +1

Ben Stiller

as Daryl Frye in The Flash DCEU

Score: +1

Michelle Harrison

as Nora Allen in The Flash DCEU

Score: +2

Rick Cosnett

as Eddie Thawne in The Flash DCEU

Score: +1

Victoria Justice

as Iris West in The Flash DCEU

Score: +5

Grant Gustin

as Flash/Barry Allen in The Flash DCEU

Score: -2

Campbell Scott

as Richard Parker in Spider-Man (2007)

Score: +3

Embeth Davidtz

as Mary Parker in Spider-Man (2007)

Score: +1

Martin Sheen

as Uncle Ben in Spider-Man (2007)

Score: +1

Meryl Streep

as Aunt May in Spider-Man (2007)

Score: +1

RJ Cyler

as Spider-Man Miles Morales/1610 in Spiderverse

Score: +1

Matthew McConaughey

as Ultimate Green Goblin Norman Osborn/1610 in Spiderverse

Score: +1

Seth Rogen

as Spider-Man 616 in Spiderverse

Score: -1

Andrew Garfield

as Spider-Man 616 in Spiderverse

Score: +2

Willem Dafoe

as Best Villain Adaptation in Best and Worst of Spider-Man

Score: +33