Suggestions by @andrewsheng

Jon Hamm

as Palmer Strickland in Strange Days genderswap

Score: +1

Elisabeth Moss

as Dwayne Engelman in Strange Days genderswap

Score: +1

Tina Fey

as Tick in Strange Days genderswap

Score: +1

Tom Cruise

as Iris in Strange Days genderswap

Score: +1

Kaitlin Olson

as Jeriko One in Strange Days genderswap

Score: +1

Anna Kendrick

as Burton Steckler in Strange Days genderswap

Score: +1

Kat Dennings

as Philo Gant in Strange Days genderswap

Score: +1

Aaron Paul

as Max Peltier in Strange Days genderswap

Score: +1

Bryan Cranston

as Faith Justin in Strange Days genderswap

Score: +1

Alfonso Ribeiro

as Lornette "Mace" Mason in Strange Days genderswap

Score: +1

Amy Poehler

as Lenny Nero in Strange Days genderswap

Score: +1

Brooke Burns

as Randi Hickey in My Name Is Earl genderswap

Score: +1

Taraji P. Henson

as Denise Turner in My Name Is Earl genderswap

Score: +1

George López

as Chris Aruca in My Name Is Earl genderswap

Score: +1

Jerry Seinfeld

as Jerry Turner in My Name Is Earl genderswap

Score: +1

Neve Campbell

as Ellen Hickey in My Name Is Earl genderswap

Score: +1

Mara Wilson

as Tilly Green in Big City Greens

Score: +1

Anna Kendrick

as Tilly Green in Big City Greens

Score: +1

Anna Kendrick

as Lisa Simpson in The Simpsons

Score: +1

Anna Kendrick

as Isabella Garcia-Shapiro in Phineas and Ferb (Live Action)

Score: 0