Fan CastingSpider-Man 5 (2011)

Peter is at its lowest as Mary Jane just died at the hands of the Vulture. Right now, he can't trust anyone, not even Felicia that, in the meantime, has turned to a new leaf and started to do good for the city. Spider-Man is nowhere to be seen and the citizens start to lose their faith in him. The only person Peter can trust is his professor and menthor Curtis Connors. The doctor has had his right arm amputed and has been trying for years to come up with a method to make it regrow. Peter decides to help him and together they develop an experimental serum taken from reptilian DNA. It works and the doctor's arm has now regrown. But the next day, Peter finds out that the DNA transformed the doctor into a giant lizard that is now terrorizing the city. Spider-Man must now rise from the ashes and defeat his menthor to try and save him from his terrible fate.