Lester suffers from a wasting disease which has gradually worn down his motor skills during his life and left him wheelchair-bound, though he is able to walk short distances with the use of a cane. Due to his limited mobility, Lester has grown considerably overweight, and he also suffers from asthma. It is implied that Lester was bullied in high school, as he posted on Bleeter that "getting revenge" on his old high school class "never seemed to get old".
Fan Casting
Rainn Wilson
Paul Giamatti
David Cross
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