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A successful physician and devoted family man, John Dolittle seems to have the world by the tail, until a long suppressed talent he possessed as a child, the ability to communicate with animals is suddenly reawakened with a vengeance! Now every creature within squawking distance wants the good doctor's advice, unleashing an outrageous chain of events that turns his world upside down!
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A group of beavers ask Dr. Dolittle to save their habitat from loggers. The only hope is to get the forest preserved because it's the home of a protected bear, but there's a problem: the bear's the only bear in the forest, so she can't reproduce. Undaunted, Dolittle persuades a circus bear to help out, but he has to teach him not just the ways of the wild, but the wiles of lady bears too.
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After losing his wife seven years earlier, the eccentric Dr. John Dolittle, famed doctor and veterinarian of Queen Victoria’s England, hermits himself away behind the high walls of Dolittle Manor with only his menagerie of exotic animals for company. But when the young queen falls gravely ill, a reluctant Dolittle is forced to set sail on an epic adventure to a mythical island in search of a cure, regaining his wit and courage as he crosses old adversaries and discovers wondrous creatures.