Fan Casting Reese Witherspoon as Francine Smith in American Dad

katiecage made this fan casting suggestion on December 27, 2023. What do you think? See below to cast your vote, or click here to see all fan casting suggestions for this role.

Reese Witherspoon as Francine Smith in American Dad

Reese WitherspoonUnited States

49 years old
Laura Jeanne Reese Witherspoon (born March 22, 1976) is an American actress and producer. She is the recipient of various accolades, including an Academy Award, a Primetime Emmy Award, and two Gold...
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American Dad

American Dad

by Seth MacFarlane, Mike Barker, Matt Weitzman
A live-action R-Rated movie revolving around. Stan Smith is a CIA agent painfully dedicated to homeland security. His home life includes doting wife Francine, a ditzy housewife, liberal daughter Ha...
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Reese Witherspoon is known for her roles in Sing, Monsters vs Aliens, and American Psycho. She has been suggested by fans for 3,160 roles on myCast, including Michellee in Green Eggs and Ham (Illumination Entertainment Version). Similar actors include Amy Adams, Kristen Bell, and Emily Blunt. Reese Witherspoon was suggested to play Francine Smith in American Dad by katiecage. Other actors sugggested to play this role include Scarlett Johansson, Angelina Jolie, and Anne Hathaway. American Dad has 12 roles, including Stan Smith, Hayley Smith, and Klaus.

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